منابع مشابه
Migration of dendritic cells across blood and lymphatic endothelial barriers.
Dendritic cells (DC) are professional antigen presenting cells which play a pivotal role in the activation of adaptive immunity. Tissue invasion by pathogens induces the recruitment of blood DC to the site of infection and contributes to their subsequent migration to secondary lymphoid organs. This complex process relies on the expression and regulation of receptors for chemotactic factors on t...
متن کاملImmune cells control skin lymphatic electrolyte homeostasis and blood pressure.
The skin interstitium sequesters excess Na+ and Cl- in salt-sensitive hypertension. Mononuclear phagocyte system (MPS) cells are recruited to the skin, sense the hypertonic electrolyte accumulation in skin, and activate the tonicity-responsive enhancer-binding protein (TONEBP, also known as NFAT5) to initiate expression and secretion of VEGFC, which enhances electrolyte clearance via cutaneous ...
متن کاملDiagnosis of Lymphatic and Immune Disorders
The lymphatic and immune systems work together to detect and destroy foreign substances and microorganisms that may disturb homeostasis. In addition, the lymphatic system aids the cardiovascular system in maintaining fluid balance. Disorders of the lymphatic system are therefore often associated with disorders of immunity and fluid balance. Such interactions must be kept in mind in the diagnosi...
متن کاملPolarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42.
We have shown previously that T1α/podoplanin is required for capillary tube formation by human lung microvascular lymphatic endothelial cells (HMVEC-LLy) and that cells with decreased podoplanin expression fail to properly activate the small GTPase RhoA shortly after the beginning of the lymphangiogenic process. The objective of this study was to determine whether podoplanin regulates HMVEC-LLy...
متن کاملAssessment of metrezoate-labeled gallium transmission in cultured human Burkitt lymphatic cells
Background: In addition to determining the exact tumor location and its geometric features, an increase of the effective tumor atomic number will enhances the chance in treating the tumoral cells under suitable radiation. In the present study, we assessed metrezoate-labeled gallium transmission in Burkett lymphatic cells. Materials and Methods: Human Burkitt lymphatic cells were grown ...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2019
ISSN: 1664-3224
DOI: 10.3389/fimmu.2019.01168